Developmental BiologyCirculation ResearchPeer-reviewed
KMT2D-NOTCH Mediates Coronary Abnormalities in Hypoplastic Left Heart Syndrome
Zhiyun Yu, Xin Zhou, Ziyi Liu…·Mingxia Gu
This study identifies KMT2D-NOTCH signaling defects in HLHS coronary artery endothelial cells, showing impaired differentiation and proliferation due to suppressed NOTCH target genes.