BioinformaticsNature Cardiovascular ResearchPeer-reviewed
APOE-NOTCH Axis Governs Elastogenesis During Human Cardiac Valve Remodeling
Ziyi Liu, Yu Liu, Zhiyun Yu…·Mingxia Gu
The paper identifies a novel APOE+ elastin-producing valve interstitial cell subtype and reveals the APOE-NOTCH signaling axis regulates elastogenesis during human cardiac valve remodeling.