Nele Taba

This paper identifies novel genetic loci and polygenic risk scores for rheumatoid arthritis using a million-participant meta-analysis and shows improved risk prediction with metabolomic integration.

The paper links polygenic risk scores to gut microbiome traits using the Estonian Microbiome Cohort, identifying 282 species-level associations and suggesting microbiome mediation of genetic risk.

This study performs a large-scale GWAS on 249 metabolic traits in 619,372 individuals, identifying 88,604 associations and using MR to explore causal links between metabolites and diseases.

This study shows that circadian misalignment contributes to myopia across species, with reversible effects in mice and associations in human populations.

The paper infers parent-of-origin effects in ~265,000 individuals using a novel method, identifying over 30 novel POEs and confirming known associations, supporting the parental conflict hypothesis.

The paper reviews the Estonian Biobank's role in advancing genomics research and personalized medicine through its comprehensive data and translational focus.

The paper evaluates long-term effects of antibiotics and human-targeted medications on the gut microbiome using electronic health records and metagenomics data.

The paper uses genetic variation to assess the causal impact of food choices on health outcomes, identifying robust associations between eating patterns and several diseases.

The paper develops eleven omics-based biological age clocks with strong correlations to chronological age and shows their association with disease risk.

This study uses Mendelian randomization to identify 417 potential causal links between dietary patterns and blood metabolites, including novel associations and replication of known ones.