Author

Mamatha Bhat

University Health NetworkORCID 0000-0003-1960-8449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jüri ReimandiD· 2 shared Kevin C.L. ChengiD· 2 shared Zoe P. KleiniD· 2 shared Alexander T. BahcheliiD· 1 shared Chris McIntoshiD· 1 shared Christian A. Lee· 1 shared Daniel SchramekiD· 1 shared Diala Abd-RabboiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Jüri ReimandORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedNov 21, 2025

Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes

Liis Uusküla-Reimand, Christian A. Lee, Robin Hyunseo Oh…·Jüri Reimand

The paper identifies TOP2B binding sites as mutational hotspots in cancer genomes, showing their role in structural variants and driver mutations in genes like TP53 and MYC.

6 citations

humanwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologyMolecular Cancer ResearchPeer-reviewedSep 3, 2025

Combinations of genomic alterations and immune microenvironmental features associate with patient survival in multiple cancer types

Masroor Bayati, Zoe P. Klein, Alexander T. Bahcheli…·Jüri Reimand

The paper identifies immunogenomic interactions across 13 cancer types using a multi-omics framework, linking genomic alterations and immune features to patient survival.

3 citations

humanwhole-exome sequencing

𝕏 PostBluesky