Odile Filhol

This study identifies Nlrp6 as a regulator of DNA repair and epithelial regeneration in intestinal crypts, linking DNA damage responses to colorectal cancer progression.

This study uses 3D invasion models of RCC cell lines to predict their metastatic potential in vivo, showing that 3D models better reflect in vivo behavior than 2D assays.

The paper identifies key predictors of PD-1 blockade response in renal cell carcinoma by analyzing the tumor microenvironment of metastatic sites and developing a predictive TID score.