Author

Mathias Chamaillard

Centre National de la Recherche ScientifiqueORCID 0000-0002-0243-9717Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Iradj SobhaniiD· 2 shared Nilmara de Oliveira AlvesiD· 2 shared A. Försti· 1 shared Alice CarrieriD· 1 shared Amaury VaysseiD· 1 shared ANR. Wewer· 1 shared Audrey VincentiD· 1 shared Aurélien AmiotiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Iradj SobhaniORCID

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Author profile →

2 papers

Recent·Most cited

A crypt-operating DNA repair checkpoint for uncoupling regeneration and tumorigenesis

Richard Ruez, K. Radulovic, JJ Martinez-Torres, Olivier Boulard, Mound. Abdallah, Thomas Paz del Socorro, Giulia Nigro, Marion Seillier, Ghaffar Muharram, JJ Martinez-Garcia, François Gerbe, Emilie Floquet, Isabelle VAN SEUNINGEN, Alice Carrier, Philippe Jay, , Mathias Chamaillard

This study identifies Nlrp6 as a regulator of DNA repair and epithelial regeneration in intestinal crypts, linking DNA damage responses to colorectal cancer progression.

bioRxiv · Mar 2, 2026 · PreprintCell Biology

Poor prognosis in IBD-complicated colon cancer through gut dysbiosis-related immune response failure

Iradj Sobhani, Nilmara de Oliveira Alves, Mohammad Sadeghi, Cécile Charpy, Emma Bergsten, Aurélien Amiot, Caroline Barau, Francesco Brunetti, Amaury Vaysse, Christophe Tournigand, Mathias Chamaillard, Khashayarsha Khazaie, Denis Mestivier

This study identifies poor prognosis in IBD-related colon cancer due to gut dysbiosis and immune response failure, linked to microbial imbalance and altered gene expression.

bioRxiv · Mar 25, 2025 · PreprintImmunology