Alex R. Buckley

The paper introduces Synapse-seq, a method to link transcriptomes to synaptic architecture by using protein-guided RNA barcoding, revealing new insights into neural connectivity and cell type-specific dendritic structures.

The paper identifies a novel monosynaptic glutamatergic projection from the ventral tegmental area to the locus coeruleus that enhances aversive processing through synaptic integration during salient stimuli.

The paper uses whole brain imaging to compare amyloid beta deposition patterns in three Alzheimer's disease mouse models, revealing distinct spatial distributions across brain regions.