Jeffrey G. Tasker

This study identifies a PV-driven oscillatory switch in the amygdala that governs valence assignment through noradrenergic modulation.

The paper shows that NE activates CCK interneurons in the BLA to generate rhythmic inhibitory input, reducing fear memory through enhanced theta oscillations.

This study shows glucocorticoids rapidly desensitize CRH neurons to norepinephrine by regulating α1 adrenoreceptor trafficking through nitrosylation and endocytosis.

The paper identifies a non-canonical cortico-amygdala pathway from the dorsal peduncular prefrontal cortex to the central amygdala that regulates high-intensity defensive behaviors like flight.

This paper develops a dual valence operant conditioning paradigm to study appetitive and aversive behaviors in mice and tests the role of central amygdala neurons in these responses.

The paper investigates how neuromodulation of parvalbumin interneurons in the basolateral amygdala affects network and behavioral states during fear expression.

The paper shows that acute stress reduces the response of CRH neurons to norepinephrine and physiological stress through glucocorticoid-mediated adrenoreceptor desensitization.

The paper reveals a novel retrograde signaling mechanism in CRF neurons where astrocytes amplify dendritic volume transmission by responding to norepinephrine-induced ATP release.