Shyam Kumar Masakapalli

This study uses isotopic tracing to analyze metabolic differences in Mtb-infected cells, showing virulent and drug-resistant strains have distinct metabolic dependencies.

This study identifies transcriptomic changes in A549 lung cancer cells as they transition from non-confluent to confluent growth, revealing shifts in metabolic pathways and transporters.

This study uses metabolomics to analyze potato leaf metabolism during Alternaria solani infection, identifying key metabolic changes and defense markers.

This study investigates how exogenous GABA and succinate affect metabolic pathways and nodule formation in pea plants, showing GABA alters TCA cycle intermediates and increases nitrogen content.

This study investigates physicochemical and metabolic changes in apple fruits infected with Apple scar skin viroid, identifying tissue-specific metabolic reprogramming and potential biomarkers for disease diagnosis.

The paper identifies age-associated aggregation-prone proteins in C. elegans and evaluates phytochemicals targeting conserved proteins, finding quercetin as a strong binder but no significant effect on protein insolubility.

This study uses genome-scale metabolic modeling and 13C-based pathway mapping to identify key enzymes for enhancing camptothecin production in the endophyte Alternaria burnsii.

The paper investigates how different light wavelengths affect metabolite levels in two Amaranthus tricolor cultivars using GC-MS, finding cultivar-specific metabolic changes.

This study identifies drought-responsive metabolites in potato leaves that can serve as biomarkers to improve irrigation advisories in heterogeneous agricultural settings.

This study uses 13CO2 tracing to compare metabolic transitions in Brassica napus seedlings under visible and UV-B light, revealing distinct carbon assimilation and biosynthesis patterns during light-to-dark transitions.

This study shows methionine supplementation enhances pro-inflammatory responses and mycobacterial clearance in tuberculosis by modulating host metabolism and epigenetic pathways.

This study profiles secondary metabolites in red and pink Rhododendron petals using MS and NMR, identifying bioactive compounds like quinic acid and flavonoids.

This study identifies BBX31/miP1b-mediated metabolic changes in Arabidopsis under UV-B stress using metabolomics and 13CO2 tracing, showing increased phenylalanine and other protective metabolites.

This study uses a kinetic 13C dilution strategy to analyze oleate metabolism in E. coli and shows that arcA knockout enhances oleate utilization and metabolic reprogramming.

This paper identifies the Entner-Doudoroff pathway and Non-OxPPP as the main metabolic routes in Ralstonia solanacearum, bypassing glycolysis and OxPPP during glucose oxidation, using 13C labeling and comparative metabolic network analysis.