Author

Catarina Martins‐Costa

Institute of Molecular BiotechnologyORCID 0000-0003-2018-898XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:trajectory inference· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Angela Maria Peer· 3 shared Juergen A. KnoblichiD· 3 shared Nina S. CorsiniiD· 3 shared Gregor J. KasprianiD· 2 shared Jaydeep SidhayeiD· 2 shared Maria NovatchkovaiD· 2 shared Marlene StuempfleniD· 2 shared Paul Möseneder· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersDevelopmental Biology

Angela Maria Peer

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3 papers

Recent·Most cited

Developmental BiologyNaturePeer-reviewedSep 13, 2023

Single-cell brain organoid screening identifies developmental defects in autism

Chong V. Li, Jonas Simon Fleck, Catarina Martins‐Costa…·Juergen A. Knoblich

The paper uses CRISPR and single-cell transcriptomics to screen ASD risk genes in brain organoids, identifying developmental defects and regulatory modules linked to autism.

288 citationstop 1%

humanscRNA-seq

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NeurosciencebioRxivPreprintMay 4, 2023

ARID1B controls transcriptional programs of axon projection in the human corpus callosum

Catarina Martins‐Costa, Vincent A. Pham, Andrea Wiegers…·Juergen A. Knoblich

This study identifies ARID1B's role in axon projection of callosal projection neurons, showing its haploinsufficiency leads to structural underconnectivity and agenesis of the corpus callosum.

5 citations

humanexperimental assay

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Developmental BiologybioRxivPreprintDec 6, 2022

Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous ECM

Catarina Martins‐Costa, Vincent A. Pham, Jaydeep Sidhaye…·Juergen A. Knoblich

This study compares the effects of exogenous and endogenous ECM on neuroepithelial development in human telencephalic organoids, showing rapid polarization with exogenous ECM and gradual acquisition with endogenous ECM.

6 citations

humanspatial transcriptomics

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