Author

Angela Maria Peer

Institute of Molecular Biotechnology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:gene regulatory network inference· 2 Assay:spatial transcriptomics· 2 Research Focus:trajectory inference· 2 Research Focus:clustering· 1

Frequent Co-Authors

Juergen A. KnoblichiD· 4 shared Nina S. CorsiniiD· 4 shared Catarina Martins‐CostaiD· 3 shared Maria NovatchkovaiD· 3 shared Ábel VértesyiD· 2 shared Gregor J. KasprianiD· 2 shared Jaydeep SidhayeiD· 2 shared Marlene StuempfleniD· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersDevelopmental Biology

Juergen A. KnoblichORCID

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4 papers

Recent·Most cited

Single-cell brain organoid screening identifies developmental defects in autism

Chong V. Li, Jonas Simon Fleck, Catarina Martins‐Costa, Thomas Rainer Burkard, Jan Themann, Marlene Stuempflen, Angela Maria Peer, Ábel Vértesy, Jamie B. Littleboy, Christopher Esk, Ulrich Elling, Gregor J. Kasprian, Nina S. Corsini, Barbara Treutlein, Juergen A. Knoblich

The paper uses CRISPR and single-cell transcriptomics to screen ASD risk genes in brain organoids, identifying developmental defects and regulatory modules linked to autism.

Nature · Sep 13, 2023Peer-reviewedDevelopmental Biology

ARID1B controls transcriptional programs of axon projection in the human corpus callosum

Catarina Martins‐Costa, Vincent A. Pham, Andrea Wiegers, Jaydeep Sidhaye, Balint Doleschall, Maria Novatchkova, Thomas Lendl, Marielle Piber, Angela Maria Peer, Paul Möseneder, Marlene Stuempflen, Siu Yu A. Chow, Rainer Seidl, Daniela Prayer, Romana Höftberger, , Juergen A. Knoblich

This study identifies ARID1B's role in axon projection of callosal projection neurons, showing its haploinsufficiency leads to structural underconnectivity and agenesis of the corpus callosum.

bioRxiv · May 4, 2023 · PreprintNeuroscience

Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous ECM

Catarina Martins‐Costa, Vincent A. Pham, Jaydeep Sidhaye, Maria Novatchkova, Angela Maria Peer, Paul Möseneder, Nina S. Corsini, Juergen A. Knoblich

This study compares the effects of exogenous and endogenous ECM on neuroepithelial development in human telencephalic organoids, showing rapid polarization with exogenous ECM and gradual acquisition with endogenous ECM.

bioRxiv · Dec 6, 2022 · PreprintDevelopmental Biology

Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex

Oliver L. Eichmüller, Nina S. Corsini, Ábel Vértesy, Ilaria Morassut, Theresa Scholl, Victoria‐Elisabeth Gruber, Angela Maria Peer, Julia S. F. Chu, Maria Novatchkova, Johannes Andreas Hainfellner, Mercedes F. Paredes, Martha Feucht, Juergen A. Knoblich

This study uses cerebral organoids to show that TSC2 mutations cause over-proliferation of caudal late interneuron progenitors, leading to Tuberous Sclerosis Complex.

Science · Jan 27, 2022Peer-reviewedNeuroscience