Author

Luis Alberto Vega

Memorial HermannORCID 0000-0003-2031-865XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Anthony R. FloresiD· 3 shared Piyali MukherjeeiD· 2 shared Samuel A. ShelburneiD· 2 shared Anne E. Hohlt· 1 shared Chioma OdoiD· 1 shared Gretchen A. Morrison· 1 shared Gretchen Morrison· 1 shared Jennifer Angeline GaddyiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

Anthony R. FloresORCID

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3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedAug 4, 2026

SpxA1 and SpxA2 Function as a Stoichiometry-Dependent Regulatory Rheostat Governing Virulence Gene Expression in Group A Streptococcus

Gretchen A. Morrison, Luis Alberto Vega, Misu Ailin Sanson Iglesias…·Anthony R. Flores

This study identifies SpxA1 and SpxA2 as regulators of virulence gene expression in GAS, showing their stoichiometric balance determines transcriptional programs through interactions with CovR.

DOI 10.1128/mbio.01650-26

humanbulk RNA-seq

𝕏 PostBluesky

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedNov 13, 2024

LiaR-dependent gene expression contributes to antimicrobial responses in group A Streptococcus

Luis Alberto Vega, Misu A. Sanson, Piyali Mukherjee…·Anthony R. Flores

This study identifies the LiaFSR regulon in Group A Streptococcus and shows how phosphorylated LiaR regulates virulence and AMP resistance via SpxA2 and other genes.

9 citations

bacteria (other)DNA methylation

𝕏 PostBluesky

MicrobiologyInfection and ImmunityPeer-reviewedJun 18, 2024

Emergent emm4 group A Streptococcus evidences a survival strategy during interaction with immune effector cells

Chioma Odo, Luis Alberto Vega, Piyali Mukherjee…·Samuel A. Shelburne

This study identifies a survival strategy in emm4 group A Streptococcus strains through downregulation of SLO and upregulation of msrAB, enabling better macrophage survival without increased virulence.

4 citations

humanexperimental assay

𝕏 PostBluesky