Author

Rafael Queiroz de Souza

Universidade de São PauloORCID 0000-0003-2049-4565Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Amanda Verdicchio Caniato· 1 shared Karina Ramalho BortoluciiD· 1 shared Luiza Zainotti Miguel Fahur BottinoiD· 1 shared Mariana de Jesus Dias· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

Amanda Verdicchio Caniato

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJun 1, 2026

Opposing roles of GSDMD and NINJ1 shape early IL-1β dependent host defense during Toxoplasma gondii infection

Rafael Queiroz de Souza, Amanda Verdicchio Caniato, Luiza Zainotti Miguel Fahur Bottino…·Karina Ramalho Bortoluci

This study shows that GSDMD limits host resistance to Toxoplasma gondii while NINJ1 promotes protection, revealing opposing roles of pyroptotic effectors in IL-1β-dependent immunity.

DOI 10.64898/2026.05.28.728484

mousehuman

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