Author
Czech Academy of Sciences, Institute of Organic Chemistry and BiochemistryORCID 0000-0003-2053-9428Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Anna Kertisová, Shang‐Wu Shih, Nicholas S. Kirk…·Irena Selicharová
This study develops synthetic PAPP-A inhibitors that modulate IGF signaling in vitro and in vivo, showing efficacy comparable to natural inhibitors.
Nikolai Chetverikov, Eszter Szánti‐Pintér, Jan Jurica…·Eva Kudová
This paper introduces TQ1 probes to map non-canonical cholesterol-binding sites on the M1 muscarinic receptor, showing improved quenching and binding specificity compared to Dabcyl.
Santosh Kumar Adla, Barbora Hrčka Krausová, Bohdan Kysilov…·Eva Kudová
This study identifies potent NMDAR positive modulators by modifying the pregnenolone scaffold with C-20 oxime ethers, showing improved efficacy and drug-like properties compared to PES.