Li Li

This study shows that ascorbate and TET2 promote balanced hematopoiesis, which is essential for surviving malaria and reducing disease severity.

This study shows that ascorbate deficiency in hematopoietic cells promotes leukemogenesis and identifies ascorbate as a tumor suppressor metabolite in blood cancers.

This study shows that TCA cycle turning is not essential for stem and progenitor cell survival or proliferation and its loss enhances stem cell function in hematopoiesis.

This study uses cryo-EM to reveal structural polymorphism in ex-vivo ALECT2 amyloid fibrils, identifying three morphologies and acetylation sites.

This study shows that ascorbate deficiency protects mice from schistosomiasis by impairing schistosome egg production and reducing disease severity.