Author

Yafeng Li

Children's Medical CenterORCID 0000-0002-1024-6990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Edward Owusu KwartengiD· 3 shared Michalis AgathocleousiD· 3 shared Ji Hyung JuniD· 2 shared Joseph Rose· 2 shared Li LiiD· 2 shared Zhiyu ZhaoiD· 2 shared Amanda R. ReyesiD· 1 shared Brayden FolgeriD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

Edward Owusu KwartengORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Leptin Receptor+ cells create a perisinusoidal niche for thrombopoiesis in the bone marrow by synthesizing CXCL14

Yuanyuan Xue, Ruixuan Zhang, Maowu Luo, Amanda R. Reyes, Salma Merchant, Trevor S. Tippetts, Gerik Grabowski, Tai Ngo, Y. Zhang, Zhiguo Shang, Nisi Jiang, Nathaniel S. Tjahjono, Elise C. Jeffery, Yafeng Li, Tao Wei, , Sean J. Morrison

The paper identifies LepR+ cells as a niche for thrombopoiesis by producing CXCL14, which regulates lipid metabolism and terminal differentiation in megakaryocytes.

bioRxiv · Oct 5, 2026 · PreprintCell Biology

Loss of TCA cycle turning promotes stem cell function

Yafeng Li, Joseph Rose, Edward Owusu Kwarteng, Xiaotong Yang, Jacob Zielke, Li Li, Zhiyu Zhao, Ji Hyung Jun, Michalis Agathocleous

This study shows that TCA cycle turning is not essential for stem and progenitor cell survival or proliferation and its loss enhances stem cell function in hematopoiesis.

bioRxiv · Sep 23, 2026 · PreprintBiochemistry

Stem cell function in vivo is supported by an alternative glycolysis endpoint

Edward Owusu Kwarteng, Yafeng Li, Dieu Linh Nguyen, Michalis Agathocleous

This study shows that hematopoietic stem cells (HSCs) do not require fermentation or oxidation for survival and function, instead terminating glycolysis through pyruvate export.

bioRxiv · Apr 1, 2026 · PreprintBiochemistry

Loss of vitamin C biosynthesis protects from a parasitic infection

Gongwen Chen, Ji Hyung Jun, Tobias Wijshake, Edward Owusu Kwarteng, Yunyang Li, Minwei Yuan, Joseph Rose, Shan Li, Sarah A. Cobb, Willow Serpa, Brayden Folger, Yafeng Li, L. Li, Weina Chen, James J. Collins, , Michalis Agathocleous

This study shows that ascorbate deficiency protects mice from schistosomiasis by impairing schistosome egg production and reducing disease severity.

Proceedings of the National Academy of Sciences · Dec 23, 2025Peer-reviewedBiochemistry