Mariel R. Mendoza

This study shows ACSS2-mediated histone acetylation is critical for learning and memory in a mouse AD model, with acetate supplementation rescuing deficits.

The paper quantifies tissue-specific protein turnover rates in mouse fetuses using in utero isotopic amino acid injection and proteomic analysis.

This study shows that inhibiting Acss2 reduces fear memory formation and anxiety in mice and rats by decreasing histone acetylation and gene expression in the hippocampus.