BioengineeringbioRxivPreprint
Mitochondrial genome editing reveals the impact of complex I heteroplasmic variants on human neurogenesis
Isabella Tolle, Claudio Fiorini, Jochen Dobner…·Alessandro Prigione
This study edits mtDNA variants in human iPSCs to show that heteroplasmic complex I variants impair neuronal commitment.
DOI 10.64898/2026.10.28.762518