Author

Alberto Danese

University of FerraraORCID 0000-0002-0833-9987Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Paolo PintoniD· 2 shared Simone PatergnaniiD· 2 shared Alberto Pietro PastiiD· 1 shared Alessandra MarescaiD· 1 shared Alessandro Rapone· 1 shared Anu SuomalaineniD· 1 shared Benjamin DelpratiD· 1 shared Chantal CazevieilleiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Paolo PintonORCID

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2 papers

Recent·Most cited

Cell-free mtDNA drives pyroptosis and inflammation in m.3243A>G mitochondrial disease models

Monica Moresco, Alessandro Rapone, Concetta Valentina Tropeano, Mariantonietta Capristo, Giada Capirossi, Danara Ormanbekova, Claudio Fiorini, Alberto Pietro Pasti, Francesco Valle, Alberto Danese, Simone Patergnani, Leonardo Caporali, Chiara La Morgia, Anu Suomalainen, Paolo Pinton, , Alessandra Maresca

This study shows that the m.3243A>G mutation increases cell-free mtDNA release, triggering pyroptosis and inflammation in MELAS models.

bioRxiv · Jul 1, 2026 · PreprintCell Biology

The Wolfram-like variant WFS1E864K destabilizes MAM and compromises autophagy and mitophagy in human and mice.

Simone Patergnani, Méghane S. Bataillard, Alberto Danese, Stacy Alves, Chantal Cazevieille, René Valéro, Lisbeth Tranebjærg, Tangui Maurice, Paolo Pinton, Benjamin Delprat, Élodie M. Richard

This study shows that the WFS1E864K variant reduces MAM integrity and disrupts autophagy and mitophagy in human and mouse models of Wolfram-like syndrome.

bioRxiv · Nov 16, 2023 · PreprintNeuroscience