Author

Brittany A. Petros

Broad InstituteORCID 0000-0003-2110-7475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:sequence-to-function modeling· 1 Approach:statistical model· 1

Frequent Co-Authors

Cameron MyhrvoldiD· 1 shared Hayden C. MetskyiD· 1 shared Nicole L. WelchiD· 1 shared Pardis Christine SabetiiD· 1 shared Priya P. PillaiiD· 1 shared Sreekar MantenaiD· 1 shared

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2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperGenomics

Cameron MyhrvoldORCID

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1 paper

Recent·Most cited

GenomicsNature BiotechnologyPeer-reviewedOct 11, 2024

Model-directed generation of CRISPR-Cas13a guide RNAs designs artificial sequences that improve nucleic acid detection

Sreekar Mantena, Priya P. Pillai, Brittany A. Petros…·Hayden C. Metsky

This paper designs artificial CRISPR-Cas13a guide RNAs using model-directed algorithms, showing improved sensitivity and variant discrimination in nucleic acid detection.

41 citationstop 2%

CRISPR screendeep learning

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