Author

Priya P. Pillai

Broad InstituteORCID 0000-0002-3760-2166Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:sequence-to-function modeling· 1 Approach:statistical model· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Cameron MyhrvoldiD· 2 shared Hayden C. MetskyiD· 2 shared Nicole L. WelchiD· 2 shared Pardis Christine SabetiiD· 2 shared Sreekar MantenaiD· 2 shared Brittany A. PetrosiD· 1 shared Cheri M. AckermaniD· 1 shared David K. YangiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenomics

Cameron MyhrvoldORCID

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2 papers

Recent·Most cited

GenomicsNature BiotechnologyPeer-reviewedOct 11, 2024

Model-directed generation of CRISPR-Cas13a guide RNAs designs artificial sequences that improve nucleic acid detection

Sreekar Mantena, Priya P. Pillai, Brittany A. Petros…·Hayden C. Metsky

This paper designs artificial CRISPR-Cas13a guide RNAs using model-directed algorithms, showing improved sensitivity and variant discrimination in nucleic acid detection.

41 citationstop 2%

CRISPR screendeep learning

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GenomicsNature BiotechnologyPeer-reviewedMar 3, 2022

Designing viral diagnostics with model-based optimization

Hayden C. Metsky, Nicole L. Welch, Priya P. Pillai…·Pardis Christine Sabeti

This paper designs viral diagnostics using a model-based optimization approach, achieving higher sensitivity and specificity across viral genomic variation.

121 citationstop 2%

virusDNA methylation

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