Author

Alexander A. Choi

QB3ORCID 0000-0003-2119-8995Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Ke XuiD· 2 shared Ayana TaboiD· 1 shared Bret A. Unger· 1 shared Changdong He· 1 shared Chun Ying Wu· 1 shared Coral Y. ZhouiD· 1 shared Emmy LiiD· 1 shared Jon BezneyiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

Ke XuORCID

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Author profile →

3 papers

Recent·Most cited

BioengineeringbioRxivPreprintApr 5, 2025

Perturbing RNA localization for functional study in neurons

Mengting Han, Maylin L. Fu, Yanyu Zhu…·Lei S. Qi

This study introduces CRISPR-TO to manipulate RNA localization in neurons, showing it affects neurite outgrowth and axonal regeneration.

DOI 10.1101/2025.04.05.646707

𝕏 PostBluesky

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedDec 5, 2024

Single-molecule diffusivity quantification in Xenopus egg extracts elucidates physicochemical properties of the cytoplasm

Alexander A. Choi, Coral Y. Zhou, Ayana Tabo…·Ke Xu

The paper quantifies single-molecule diffusivity in Xenopus egg extracts to reveal the cytoplasm's physicochemical properties, showing charge-dependent diffusion and the role of RNA and actin.

8 citations

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 8, 2024

Hypersensitivity of the vimentin cytoskeleton to net-charge states and Coulomb repulsion

Bret A. Unger, Chun Ying Wu, Alexander A. Choi…·Ke Xu

This study shows that vimentin cytoskeleton assembly is sensitive to net charge states and Coulomb repulsion, with hypotonic stress causing rapid disassembly due to reduced charge screening.

1 citation

𝕏 PostBluesky