Author

Xinxin Chi

Harvard UniversityORCID 0000-0003-2120-6684Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Christophe O. BenoistiD· 2 shared Adélaïde GélineauiD· 1 shared Antoine FreuchetiD· 1 shared Charlotte H. WangiD· 1 shared Charlotte J. ImianowskiiD· 1 shared Chrysothemis C. BrowniD· 1 shared Dario A.A. VignaliiD· 1 shared David L Owen· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Christophe O. BenoistORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 2, 2026

A Reference Landscape of Regulatory T Cell States in Mice

Antoine Freuchet, Nitya Mehrotra, Ian Magill…·the immgenT project

The paper defines a unified framework for Treg heterogeneity using a joint RNA-protein model, identifying eight conserved clusters across tissues and conditions.

DOI 10.64898/2026.01.30.702856

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 20, 2025

Decoding Peripheral Tolerance: TCR Rules for pTreg differentiation in the Gut

Xinxin Chi, Charlotte H. Wang, Yollanda Franco Parisotto…·Christophe O. Benoist

The paper shows that TCRs from Tregs are more effective than Tconv TCRs in driving pTreg differentiation, with distinct phenotypes based on antigen type.

3 citations

mousegenetic perturbation / CRISPR

𝕏 PostBluesky