Sergio Romero‐Romero

This study investigates how antidepressants interact with LPA3 receptors through functional assays and docking simulations, revealing distinct effects on calcium and ERK 1/2 signaling.

The paper identifies two distinct agonist binding cavities in the LPA3 receptor through docking and functional studies, showing differential ligand interactions and mutation sensitivity.

This study identifies interchain electrostatic interactions as critical for collagen triple helix folding, showing their conservation across domains of life and viruses.

This study uses generative language models to design de novo triosephosphate isomerases, which show catalytic activity in E. coli.