Author

Leon Palao

University of PennsylvaniaORCID 0000-0003-2145-758XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

An XuiD· 1 shared Dung‐Fang LeeiD· 1 shared Hee Jong KimiD· 1 shared Hsiang-Ching TsengiD· 1 shared Hui-Chi Tang· 1 shared Kenji MurakamiiD· 1 shared Kuang‐Lei TsaiiD· 1 shared Mo-Fan HuangiD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

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1 paper

Recent·Most cited

BiochemistryMolecular CellPeer-reviewedSep 24, 2024

Structural basis of the human transcriptional Mediator complex modulated by its dissociable Kinase module

Ti‐Chun Chao, Shin-Fu Chen, Hee Jong Kim…·Kuang‐Lei Tsai

This study presents cryo-EM structures of the human Mediator complex and its CKM module, revealing how the CKM inhibits transcription by blocking Pol II and PIC assembly.

33 citationstop 5%

humancryo-EM

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