Author

Dung‐Fang Lee

The University of Texas MD Anderson Cancer CenterORCID 0000-0003-2387-597XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

Mo-Fan HuangiD· 2 shared Wenbo LiiD· 2 shared Agata Sekrecka· 1 shared An XuiD· 1 shared András RabiD· 1 shared Andres D. Chamorro-Parejo· 1 shared Angela H. TingiD· 1 shared Barbara Tabak· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

Mo-Fan HuangORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 1, 2025

Generation of Region-specific Airway Basal Stem Cells from Human Pluripotent Stem Cells via Regulation of NOGGIN-BMP Axis

Shingo Suzuki, Nicole Sandoval, Shnutez Doddipalli…·Sarah X.L. Huang

This study generates region-specific airway basal stem cells from human pluripotent stem cells by modulating the NOGGIN-BMP axis, showing distinct differentiation potentials for proximal and distal airway cell types.

2 citations

humanorganoid / primary culture

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 4, 2025

A TP53 Intron-Derived Peptide Promotes Tumor Survival

Louis A. Cadena, Kevin Lee Luo, Sofia M. Fernandez…·Shih‐Han Lee

The paper identifies an intronic APA-derived protein, IPADP1, that promotes cancer cell survival and tumor formation in leukemia.

DOI 10.1101/2025.09.04.674312

humanproteomics

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Molecular BiologybioRxivPreprintMar 22, 2025

Rewired m6A methylation of promoter antisense RNAs in Alzheimer disease regulates global gene transcription in the 3D nucleome

Benxia Hu, Yuqiang Shi, Feng Xiong…·Wenbo Li

The paper identifies AD-associated changes in m6A methylation on promoter antisense RNAs and shows their role in regulating gene expression and neuronal survival in Alzheimer's disease.

DOI 10.1101/2025.03.22.644756

humanbulk RNA-seq

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BiochemistryMolecular CellPeer-reviewedSep 24, 2024

Structural basis of the human transcriptional Mediator complex modulated by its dissociable Kinase module

Ti‐Chun Chao, Shin-Fu Chen, Hee Jong Kim…·Kuang‐Lei Tsai

This study presents cryo-EM structures of the human Mediator complex and its CKM module, revealing how the CKM inhibits transcription by blocking Pol II and PIC assembly.

33 citationstop 5%

humancryo-EM

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