David Cameron Wraith

This paper uses intradermal GAD-Alum challenge and scRNA-seq to identify and profile GAD-reactive T cells in type 1 diabetes.

This study uses a magnetic particle-based platform to mechanically modulate T-cell receptors, showing that NFAT pathway signaling accumulation is required for CD4+ T cell activation.

This study shows that IFNγ and IL-27 enhance Tr1 cell development during strong TCR signaling in a mouse model.