Yuhao Zhong

This paper introduces BALT-seq, a one-step chemoselective method for hydroxymethylcytosine profiling in DNA and RNA, showing high concordance with existing methods and improved RNA enrichment.

The paper reveals an m6A-dependent mechanism where microRNAs bind chromatin-associated RNAs to activate transcription by recruiting chromatin remodelers and demethylases.

This paper introduces DR-6mA-seq, a method to detect 6mA at single-base resolution in mammalian genomes, finding low abundance in most tissues but distinct sites in mouse testis and glioblastoma cells.