Chenkai Ma

This paper introduces MDBrainT, a DNA methylation-based deconvolution method to predict cell composition in brain tumor microenvironments, revealing distinct patterns across tumor types and molecular subtypes that correlate with patient outcomes.

This paper shows that a CXCR4 partial agonist enhances immunotherapy in gastric cancer by targeting PMN-MDSCs and granulopoiesis.

The paper compares methylation levels measured by four methods in GC-rich regions and finds that EM-seq and ONT show less GC bias than WGBS and EPIC.

The paper identifies miR-143 as a protective miRNA in ischemia-induced retinal neovascularization using miRNA-Seq and RNA-Seq in a rat model.