Author

Joanne E. Falck

German Center for Neurodegenerative DiseasesORCID 0000-0003-2185-3750Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:rat· 3 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Craig Curtis GarneriD· 2 shared Dietmar SchmitziD· 2 shared Frauke AckermanniD· 2 shared Alberto AntoniettiiD· 1 shared Alex M. Thomson· 1 shared Alexis ArnaudoniD· 1 shared András EckeriD· 1 shared Anna-Kristin KaufmanniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Craig Curtis GarnerORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 3, 2025

Piccolo Regulates Secretion of the Extracellular Matrix Components Brevican and Tenascin R from Astrocytes to Drive Synapse Formation: Implications for Pontocerebellar Hypoplasia Type 3 (PCH3)

Maryam Mohamaddokht, Joanne E. Falck, Sanra Kumsal Öktem…·Frauke Ackermann

This study identifies Piccolo's role in astrocytic ECM secretion, showing its impact on synapse formation and neuronal network activity in PCH3.

DOI 10.1101/2025.07.03.662734

ratbulk RNA-seq

𝕏 PostBluesky

NeurosciencePLoS BiologyPeer-reviewedNov 5, 2024

Community-based Reconstruction and Simulation of a Full-scale Model of Region CA1 of Rat Hippocampus

Armando Romani, Alberto Antonietti, Davide Bella…·Henry Markram

The paper presents a full-scale in silico model of rat hippocampal CA1 integrating diverse experimental data and validates it through simulations of theta rhythm and other experiments.

39 citationstop 1%

𝕏 PostBluesky

NeuroscienceJournal of NeurosciencePeer-reviewedMar 2, 2020

Loss of Piccolo function in rats induces Pontocerebellar Hypoplasia type 3-like phenotypes

Joanne E. Falck, Christine Bruns, Sheila Hoffmann-Conaway…·Frauke Ackermann

This study shows that Piccolo knockout rats exhibit anatomical and behavioral features similar to Pontocerebellar Hypoplasia type 3, supporting a causal link between Piccolo function and PCH3.

16 citations

ratexperimental assay

𝕏 PostBluesky