Craig Curtis Garner

The paper uses mRNA-engineered dendritic cells to detect AQP4-specific T cell responses in NMOSD patients, showing strong activation in a patient with recent disease activity.

This study identifies Piccolo's role in astrocytic ECM secretion, showing its impact on synapse formation and neuronal network activity in PCH3.

This study investigates the role of piccolino in cochlear inner hair cell synapses, finding it contributes to active zone organization and is essential for normal synaptic transmission.

The paper demonstrates that patient-derived monoclonal GABAA receptor antibodies cause catatonia and seizures in rodents, providing a model for autoimmune encephalitis and supporting antibody depletion as a treatment.

The paper identifies Pclo mutations in rats that affect reproductive behavior and link to depression-associated genes.

This study shows that Piccolo knockout rats exhibit anatomical and behavioral features similar to Pontocerebellar Hypoplasia type 3, supporting a causal link between Piccolo function and PCH3.

This study shows Piccolo is essential for synaptic vesicle recycling through Pra1 and Rab5, linking its dysfunction to neurological disorders.

This study uses light-induced ROS to control SV protein damage and shows that autophagy rapidly clears damaged proteins in mouse hippocampal neurons, maintaining synaptic function.