Author

Hongkai Zhang

Nankai UniversityORCID 0000-0003-2186-5508Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alexander G. GabiboviD· 1 shared Alexey V. StepanoviD· 1 shared Daria S. OsipovaiD· 1 shared Ding ZhangiD· 1 shared Dmitry PershiniD· 1 shared Dmitry V. VolkoviD· 1 shared Ekaterina A. MalakhovaiD· 1 shared Elena A. KulakovskayaiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexander G. GabibovORCID

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1 paper

Recent·Most cited

Molecular BiologyMolecular Therapy OncologyPeer-reviewedJun 27, 2024

Targeting CD45 by gene-edited CAR-T cells for leukemia eradication and hematopoietic stem cell transplantation preconditioning

Valeria M. Stepanova, Dmitry V. Volkov, Daria S. Osipova…·Alexey V. Stepanov

This paper demonstrates the preclinical efficacy of CD45-targeting CAR T and NK cells for leukemia treatment and HSCT preconditioning, showing reduced fratricide through gene editing.

9 citations

humanexperimental assay

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