Kyuson Yun

The paper identifies a female-biased IL-17/STAT3 signaling program in microglia associated with dementia in Alzheimer's disease using single-cell transcriptomics.

This study shows that human tumor slices better predict patient responses to an oncolytic virus than mouse models, highlighting indication-specific efficacy.

This study identifies midkine (MDK) as a critical regulator of medulloblastoma growth and survival, showing that its suppression reduces tumor growth and prolongs survival in xenograft models.

This study shows that combining S100A4 and TIGIT inhibition suppresses breast cancer lung metastasis by enhancing T and NK cell activity in late-stage disease.

This paper uses CRISPR to edit Rictor in myeloid cells via lipid nanoparticles, reprogramming the tumor microenvironment to enhance anti-tumor immunity in a breast cancer liver metastasis model.

The paper presents a cloud-based platform for analyzing scRNA-seq data, enabling automated preprocessing and extensible post-processing workflows.