Author

Yaqoob Ali

Houston Methodist

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Fransisca LeonardiD· 2 shared Tyler Galbraith· 2 shared Artūras ŽiemysiD· 1 shared Chihiro Hashimoto· 1 shared Göknur KaraiD· 1 shared Hannah FlinniD· 1 shared Harlan Cook· 1 shared Jessica López EspinosaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Fransisca LeonardORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Intranasal CRISPR- lipid nanoparticles targeting MAPK9 reduce neuroinflammation after traumatic brain injury

Göknur Kara, Yaqoob Ali, Jessica López Espinosa, Peter Park, Morgan Holcomb, Hannah Flinn, Noah Taylor, Tyler Galbraith, Fransisca Leonard, Sonia Villapol

This paper develops an intranasal CRISPR-based therapy targeting MAPK9 in microglia to reduce neuroinflammation after traumatic brain injury, showing reduced inflammation and no toxicity.

bioRxiv · Apr 26, 2026 · PreprintNeuroscience

Rictor CRISPR Gene Editing by Lipid Nanoparticle Delivery Stimulates Anti-Tumor Immunity in Breast Cancer Liver Metastasis Model

Yaqoob Ali, Tyler Galbraith, Nourhan Abdelfattah, Artūras Žiemys, Thomas L. Wong, Chihiro Hashimoto, Maryam Faisal, Qian Xu, Harlan Cook, Tej Krishan Pandita, Yitian Xu, Roberto R. Rosato, Shu‐Hsia Chen, Kyuson Yun, Fransisca Leonard

This paper uses CRISPR to edit Rictor in myeloid cells via lipid nanoparticles, reprogramming the tumor microenvironment to enhance anti-tumor immunity in a breast cancer liver metastasis model.

bioRxiv · Jun 26, 2025 · PreprintBioengineering