Author

Han Nhat Tran

Beth Israel Deaconess Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

Jia-Shiun LeuiD· 2 shared Kyuson YuniD· 2 shared Nourhan AbdelfattahiD· 2 shared Thomas K. S. Wong· 2 shared Alaa Tamim· 1 shared Amanda AndersoniD· 1 shared Anthony T. PhaniD· 1 shared Barton F. HaynesiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Jia-Shiun LeuORCID

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3 papers

Recent·Most cited

Impact of RNA modification and IL-12 boosts on mRNA-LNP vaccine-elicited CD8+ T cell responses

Sampa Santra, Michelle A. Lifton, Benjamin Mildenberg, Georgeanna Morton, Han Nhat Tran, Laura L. Sutherland, Robert Parks, Whitney Edwards, Bette Korber, Anthony T. Phan, Christopher A. Hunter, Garima Dwivedi, Benjamin Davis, Justin Su, Mohamad‐Gabriel Alameh, , Barton F. Haynes

This study compares CD8+ T cell and antibody responses in non-human primates using different ratios of modified and unmodified mRNA-LNP vaccines with IL-12 boosting.

bioRxiv · Nov 1, 2026 · PreprintImmunology

Ex vivo human tumor slices more accurately predict patient responses to an oncolytic virus than in vivo mouse models

Jose Maldonado, Thomas K. S. Wong, Jia-Shiun Leu, Nourhan Abdelfattah, Han Nhat Tran, David S. Baskin, Robert Rostomily, Nestor F. Esnaola, Kristin Michelle Huntoon, Betty YS Kim, Wen Jiang, Muddassir Syed, Amanda Anderson, Preeti Marie, Alaa Tamim, , Kyuson Yun

This study shows that human tumor slices better predict patient responses to an oncolytic virus than mouse models, highlighting indication-specific efficacy.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology

Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells

Jia-Shiun Leu, Hui Deng, Han Nhat Tran, Wei Xiong, Nourhan Abdelfattah, Thomas K. S. Wong, Reece Kang, Chihiro Hashiomoto, Fransisca Leonard, Sinem Gunalp, José M. Benítez Salazar, José Maldonado, Carlo D. Cristobal, Hyun Kyoung Lee, Zhiqiang An, , Kyuson Yun

This study shows that combining S100A4 and TIGIT inhibition suppresses breast cancer lung metastasis by enhancing T and NK cell activity in late-stage disease.

Cancer Letters · Apr 8, 2026Peer-reviewedCancer Biology