Author

Quentin Defenouillère

Centre National de la Recherche ScientifiqueORCID 0000-0003-2255-4859Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Clotilde LausseliD· 2 shared Sébastien Léon AiD· 2 shared Agathe VerraesiD· 1 shared Alberto BalliniD· 1 shared Anne FriedrichiD· 1 shared Francisco Javier García-RodrígueziD· 1 shared Joseph SchachereriD· 1 shared Véronique AlbanèseiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Clotilde LausselORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedAug 11, 2022

2-deoxyglucose transiently inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity

Clotilde Laussel, Véronique Albanèse, Francisco Javier García-Rodríguez…·Sébastien Léon A

This paper investigates how 2-deoxyglucose (2DG) induces endocytosis of plasma membrane proteins in yeast, revealing a role for the Snf1/AMPK pathway and Rod1 in mediating 2DG resistance.

11 citations

yeastexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintDec 21, 2018

The regulation of HAD-like phosphatases by signaling pathways modulates cellular resistance to the metabolic inhibitor, 2-deoxyglucose

Quentin Defenouillère, Agathe Verraes, Clotilde Laussel…·Sébastien Léon A

This paper identifies Dog1 and Dog2 as 2DG detoxication enzymes in yeast, showing their regulation by signaling pathways and their role in 2DG resistance, with implications for human cancer therapy.

1 citation

yeastproteomics

𝕏 PostBluesky