Author
National Institutes of HealthORCID 0000-0003-2272-3907Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Nathan P. Manes, Fengkai Zhang, Bin Lin…·Aleksandra Nita‐Lazar
The paper develops a rule-based model of TLR4 signaling in mouse macrophages, identifies a missing negative feedback checkpoint involving TANK and IKKε, and validates its role in restraining inflammation.
Hannes Bongartz, Christopher T. Boughter, Bernadette Marrero…·Martin Meier‐Schellersheim
The paper shows macrophages use TLR4 memory and IL-10 susceptibility gating to adjust inflammation based on pathogen dynamics.
Manasi Gadkari, Jing Sun, Adrian Carcamo…·Luis Miguel Franco
The paper develops and validates hcHCR, a high-content imaging method for single-cell mRNA quantification in primary human immune cells, demonstrating its sensitivity, scalability, and multiplexing capability.
Samuel Katz, Jian Song, Kyle P. Webb…·Iain D. C. Fraser
TRIAGE integrates pathway and network methods to optimize gene hit selection from high-throughput assays, improving consistency across genome-wide studies.
Leah M. Rommereim, Ajay Suresh Akhade, Bhaskar Dutta…·Naeha Subramanian
A small increase in NOD1 expression leads to cancer-promoting changes in cell state by promoting persistent inflammation and oncogene expression.