Molecular BiologyCell ReportsPeer-reviewed
REV7/FANCV Binds to CHAMP1 and Promotes Homologous Recombination Repair
Feng Li, Prabha Sarangi, Divya Iyer…·Alan D. D’Andrea
The paper shows that REV7-CHAMP1 complex promotes homologous recombination repair by inhibiting NHEJ and TLS repair pathways, and its overexpression in tumors correlates with poor prognosis.
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