Feng Li

This study identifies the CHAMP1 complex's role in heterochromatin assembly and its enhancement of homology-directed DNA repair in specific genomic regions.

The paper shows that REV7-CHAMP1 complex promotes homologous recombination repair by inhibiting NHEJ and TLS repair pathways, and its overexpression in tumors correlates with poor prognosis.

This study identifies the Piezo-Atr-Chek1-Cdc25 pathway as an inhibitory mechanism for axon regeneration, showing that disrupting it enhances regeneration in Drosophila and mammals.

This study uses optogenetics to activate ERK and AKT signaling in Drosophila, enhancing axon regeneration and functional recovery in both PNS and CNS.