Author

Lisa A. Moreau

Harvard UniversityORCID 0000-0003-2985-0415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Alan D. D’AndreaiD· 2 shared Aleem SyediD· 1 shared Bartłomiej TomasikiD· 1 shared Connor S. ClairmontiD· 1 shared Dipanjan ChowdhuryiD· 1 shared Divya IyeriD· 1 shared Feng LiiD· 1 shared Hanrong FengiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Alan D. D’AndreaORCID

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2 papers

Recent·Most cited

Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedSep 11, 2023

Dynamics of the DYNLL1/MRE11 complex regulates DNA end resection and recruitment of the Shieldin complex to DSBs

Michelle L. Swift, Rui Zhou, Aleem Syed…·Dipanjan Chowdhury

This study shows how DYNLL1 and Shieldin regulate DNA end resection and repair pathway choice through interactions with MRE11 and 53BP1 at DSBs.

27 citations

humanexperimental assay

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Molecular BiologyCell ReportsPeer-reviewedAug 1, 2022

REV7/FANCV Binds to CHAMP1 and Promotes Homologous Recombination Repair

Feng Li, Prabha Sarangi, Divya Iyer…·Alan D. D’Andrea

The paper shows that REV7-CHAMP1 complex promotes homologous recombination repair by inhibiting NHEJ and TLS repair pathways, and its overexpression in tumors correlates with poor prognosis.

27 citations

humanexperimental assay

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