Dimitrios G. Anastasakis

The paper identifies vtRNAs as direct substrates of ELAC1 and shows ELAC1 has broader RNA substrate specificity compared to ELAC2.

RBProximity-CLIP maps RBP-RNA interactions at subcellular resolution, revealing compartment-specific targets for AGO2, YBX1, and ELAVL1.

This study identifies DDX3X's role in regulating host and viral mRNA translation during Sendai Virus infection, revealing its direct interaction with IFNB1 5'UTR and its impact on IFN-β production.

This study shows the MLLT3 YEATS domain binds both histone marks and the 7SK RNA, influencing hematopoietic lineage commitment and gene expression.

This study shows that influenza A virus exploits nuclear RNAi by inducing AGO2 accumulation and silencing type-I interferon genes, and that arsenic trioxide can counteract this effect.

This study identifies Matrin3's role in regulating CDC14B alternative splicing, which affects cell proliferation and mitotic spindle dynamics in colorectal cancer cells.

This study identifies that Keratin 19 sequesters HNRNPK in the cytoplasm, stabilizing mRNAs involved in cancer progression.