Author

Adam M. Boulton

Cleveland ClinicORCID 0000-0002-0102-9572Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Akash AhujaiD· 1 shared Akihiko YokoyamaiD· 1 shared Alyson Brown· 1 shared Amanda Reinhardt· 1 shared Amy Houghton AttawayiD· 1 shared Ashish KabraiD· 1 shared Benjamin I. LeachiD· 1 shared Bishnu Datt PantiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Akash AhujaORCID

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2 papers

Recent·Most cited

NF-kB-Dependent Transcriptional Regulation of Piezo1 Mediates Bacterial Clearance on Stiffened Lung

Erica M. Orsini, Adam M. Boulton, Susamma Abraham, Alyson Brown, Haley Ricci, Akash Ahuja, Bishnu Datt Pant, Caitlin M. Snyder, Amanda Reinhardt, Amy Houghton Attaway, Ryan J. Musich, Lisa M. Grove, Mitchell A. Olman, Vidula Vachharajani, Rachel Greenberg Scheraga

This study shows that NF-kB-dependent transcription of Piezo1 in macrophages enhances bacterial clearance during pneumonia by promoting lysosome biogenesis and stiffness-dependent phagolysosome maturation.

bioRxiv · Nov 6, 2025 · PreprintImmunology

The MLLT3 YEATS domain is a dual reader of histone marks (H3K9/18/27ac/cr) and ncRNA (7SK), linking epigenetic and RNA signaling to regulate hematopoiesis

Adam M. Boulton, Ashish Kabra, Nicholas J. Achille, Emmalee R. Adelman, Dimitrios G. Anastasakis, Felipe Beckedorff, Pradeep Reddy Cingaram, Ying Zhang, Benjamin I. Leach, Ramin Shiekhattar, Akihiko Yokoyama, Markus Hafner, María E. Figueroa, Nancy J. Zeleznik‐Le, John Hackett Bushweller

This study shows the MLLT3 YEATS domain binds both histone marks and the 7SK RNA, influencing hematopoietic lineage commitment and gene expression.

bioRxiv · Sep 1, 2025 · PreprintBiochemistry