Author

Nicholas J. Achille

Loyola University Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Emmalee R. AdelmaniD· 2 shared John Hackett BushwelleriD· 2 shared Nancy J. Zeleznik‐LeiD· 2 shared Adam M. BoultoniD· 1 shared Akihiko YokoyamaiD· 1 shared Ashish KabraiD· 1 shared Benjamin I. LeachiD· 1 shared Charles S. HemenwayiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Emmalee R. AdelmanORCID

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2 papers

Recent·Most cited

The chromatin reader protein MLLT1 is critical to maintain normal B lymphopoiesis

Janani Prakash, Nicholas J. Achille, Emmalee R. Adelman, Shubin Zhang, John Hackett Bushweller, Maria E. Figueroa, Charles S. Hemenway, Nancy J. Zeleznik‐Le

This study shows that MLLT1 is essential for normal B lymphopoiesis, as its deletion in mice leads to reduced B cell development and altered gene expression.

bioRxiv · Aug 10, 2026 · PreprintCell Biology

The MLLT3 YEATS domain is a dual reader of histone marks (H3K9/18/27ac/cr) and ncRNA (7SK), linking epigenetic and RNA signaling to regulate hematopoiesis

Adam M. Boulton, Ashish Kabra, Nicholas J. Achille, Emmalee R. Adelman, Dimitrios G. Anastasakis, Felipe Beckedorff, Pradeep Reddy Cingaram, Ying Zhang, Benjamin I. Leach, Ramin Shiekhattar, Akihiko Yokoyama, Markus Hafner, María E. Figueroa, Nancy J. Zeleznik‐Le, John Hackett Bushweller

This study shows the MLLT3 YEATS domain binds both histone marks and the 7SK RNA, influencing hematopoietic lineage commitment and gene expression.

bioRxiv · Sep 1, 2025 · PreprintBiochemistry