Author

Roshan L. Shrestha

National Institutes of HealthORCID 0000-0001-7597-9418Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Anish ThomasiD· 2 shared Mirit I. AladjemiD· 2 shared Ahsan PolashiD· 1 shared Ajit Kumar SharmaiD· 1 shared Anisha Tehim· 1 shared Anjali DhalliD· 1 shared Ashish LaliD· 1 shared Augustin LunaiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

Anish ThomasORCID

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Author profile →

3 papers

Recent·Most cited

Cancer BiologyiSciencePeer-reviewedSep 1, 2026

SCLC TumorMiner: A Genomics Platform for Small Cell Lung Cancer Precision Oncology

Fathi Elloumi, Anjali Dhall, Daiki Taniyama…·Yves G. Pommier

SCLC TumorMiner is a genomics platform that provides molecular classification, biomarker identification, and drug-response analysis for small cell lung cancer using integrated datasets from multiple institutions.

DOI 10.1016/j.isci.2026.117376

humanbulk RNA-seq

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Cancer BiologyCancer Research CommunicationsPeer-reviewedAug 26, 2026

Spindle Assembly Checkpoint Competency Determines Sensitivity to KIF18A Inhibition in Small-Cell Lung Cancer

Chiori Tabe, Rajesh Kumar, Yue Huang…·Anish Thomas

This study identifies SAC competency as the determinant of sensitivity to KIF18A inhibition in SCLC, offering a predictive biomarker for targeted therapies.

DOI 10.1158/2767-9764.crc-26-0560

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJun 8, 2022

Matrin3 regulates cell proliferation and spindle dynamics by regulating CDC14B alternative splicing

Bruna Rodrigues Muys, Roshan L. Shrestha, Dimitrios G. Anastasakis…·Ashish Lal

This study identifies Matrin3's role in regulating CDC14B alternative splicing, which affects cell proliferation and mitotic spindle dynamics in colorectal cancer cells.

DOI 10.1101/2022.06.08.495349

humanbulk RNA-seq

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