Ahsan Polash

RBProximity-CLIP Enables Subcellular Mapping of RNA-Binding Protein Interactions at Nucleotide Resolution

RBProximity-CLIP maps RBP-RNA interactions at subcellular resolution, revealing compartment-specific targets for AGO2, YBX1, and ELAVL1.

Oncofetal RNA-binding proteins of IGF2BP family suppress IRF-3 and NF-kB dependent transcription downstream of cytosolic RNA sensors

This study shows that IGF2BP family proteins suppress RNA-sensing pathways by binding TNFAIP3 mRNA, reducing innate immune signaling in AML cells.

The human DEAD-box protein DDX3X regulates host and viral mRNA translation during Sendai Virus infection

This study identifies DDX3X's role in regulating host and viral mRNA translation during Sendai Virus infection, revealing its direct interaction with IFNB1 5'UTR and its impact on IFN-β production.

PCLIPtools: A Robust Framework for Identifying RNA-Protein Interaction Sites from PAR-CLIP experiments.

PCLIPtools improves PAR-CLIP data analysis by identifying high-confidence RNA-protein interaction sites with greater precision and speed than existing tools.

The DND1-NANOS3 complex shapes the primordial germ cell transcriptome via a heptanucleotide sequence in mRNA 3'UTRs

The paper identifies an RNA sequence motif recognized by the DND1-NANOS3 complex in germ cells and shows its role in regulating mRNA expression.

MATRIN3 deficiency triggers autoinflammation via cGAS-STING activation

This study identifies MATRIN3 deficiency as a trigger for autoinflammation through cGAS-STING activation via mis-splicing of TDRD3 and R-loop formation.

Matrin3 regulates cell proliferation and spindle dynamics by regulating CDC14B alternative splicing

This study identifies Matrin3's role in regulating CDC14B alternative splicing, which affects cell proliferation and mitotic spindle dynamics in colorectal cancer cells.