Julian A. Zagalak

The paper introduces SPACE and SPACEmap to identify chromatin-associated RBPs and their interactions, revealing that many bind chromatin via intrinsically disordered regions.

The paper identifies that most intergenic RNA originates from fuzzy transcription of known genes, with a smaller portion from long non-coding RNA loci, and characterizes their transcriptional features and degradation patterns.

The paper shows that LINE repeat sequences recruit RNA-binding proteins to repress splicing and 3' end processing in introns, contributing to lineage-specific RNA processing in mammals.