Author

Aarti Singh

Royal Veterinary CollegeORCID 0000-0001-6077-1673Unclaimed ORCID profile · follow to get notified of new preprints

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Aarti Singh1 paper

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Anob M. ChakrabartiiD· 1 shared Christopher W. J. SmithiD· 1 shared Clare GoodingiD· 1 shared Danilo FaccendaiD· 1 shared Dong Xia· 1 shared Federico AgostiniiD· 1 shared Gopinath LakshmananiD· 1 shared Jan AttigiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Anob M. ChakrabartiORCID

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2 papers

Recent·Most cited

Cell BiologyPharmacological ResearchPeer-reviewedFeb 19, 2026

Mitochondria drive microglial NRLP3 inflammasome activation via TSPO

Aarti Singh, Manuel Rigon, Tong Guo…·Michelangelo Campanella

This study shows TSPO on mitochondria promotes microglial inflammasome activation by stabilizing NLR proteins, inhibiting mitophagy, and enhancing pro-inflammatory gene expression, leading to excitotoxicity.

6 citationstop 1%

mouseexperimental assay

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GenomicsCellPeer-reviewedAug 1, 2018

Heteromeric RNP assembly at LINEs controls lineage-specific RNA processing

Jan Attig, Federico Agostini, Clare Gooding…·Jernej Ule

The paper shows that LINE repeat sequences recruit RNA-binding proteins to repress splicing and 3' end processing in introns, contributing to lineage-specific RNA processing in mammals.

166 citationstop 2%

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