Author

Jan Attig

The Francis Crick InstituteORCID 0000-0002-2159-2880Unclaimed ORCID profile · follow to get notified of new preprints

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Federico AgostiniiD· 2 shared Jernej UleiD· 2 shared Julian A. ZagalakiD· 2 shared Nicholas M. LuscombeiD· 2 shared Aarti SinghiD· 1 shared Andreas WackiD· 1 shared Anob M. ChakrabartiiD· 1 shared Antoni G. WrobeliD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Federico AgostiniORCID

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3 papers

Recent·Most cited

Intergenic RNA mainly derives from nascent transcripts of known genes

Federico Agostini, Julian A. Zagalak, Jan Attig, Jernej Ule, Nicholas M. Luscombe

The paper identifies that most intergenic RNA originates from fuzzy transcription of known genes, with a smaller portion from long non-coding RNA loci, and characterizes their transcriptional features and degradation patterns.

Genome biology · May 5, 2021Peer-reviewedGenomics

Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retrovirus co-option

Kevin W. Ng, Jan Attig, William Bolland, George R. Young, Jack Major, Antoni G. Wrobel, Steve J. Gamblin, Andreas Wack, George Kassiotis

The paper identifies a novel ACE2 isoform, LTR16A1-ACE2, induced by interferon, which is non-functional and does not enhance SARS-CoV-2 infection.

Nature Genetics · Oct 19, 2020Peer-reviewedGenomics

Heteromeric RNP assembly at LINEs controls lineage-specific RNA processing

Jan Attig, Federico Agostini, Clare Gooding, Anob M. Chakrabarti, Aarti Singh, Nejc Haberman, Julian A. Zagalak, Warren Emmett, Christopher W. J. Smith, Nicholas M. Luscombe, Jernej Ule

The paper shows that LINE repeat sequences recruit RNA-binding proteins to repress splicing and 3' end processing in introns, contributing to lineage-specific RNA processing in mammals.

Cell · Aug 1, 2018Peer-reviewedGenomics