Wentao Li

The paper uses tXR-seq to study AFB1-induced DNA repair in the human genome, finding that 3D organization influences repair efficiency and that transcription-coupled repair is dominant.

The paper analyzes mtDNA damage fragments from three species after UV exposure, finding characteristic length profiles and di-pyrimidine patterns suggesting novel repair mechanisms.

The paper identifies UV-induced DNA repair hotspots in the human genome using XR-seq and Damage-seq, showing they are associated with chromatin states and early-replication domains.