Grégory Resch

Second-order kinetics describe systemic clearance of therapeutic bacteriophages

This study shows that therapeutic bacteriophages clear from the body following second-order kinetics, challenging first-order assumptions and informing dose design.

Phage Endolysin Enables Targeted Manipulation of the Small Intestinal Microbiota and Uncovers Niche Overlap Between Oral and Butyrate-Producing Taxa

This study uses a phage endolysin to target Streptococcus salivarius in the gut, revealing niche overlap with butyrate-producing taxa and potential therapeutic benefits.

Engraftment of donor phageome via fecal microbiota transplantation in recurrent C. difficile infection: a prospective observational study

This study evaluates phage community preservation during FMT production and engraftment in patients with rCDI, finding donor phages persist in recipients.